SCIENCE WITHOUT BORDERS PROGRAM Foreign Researcher Curriculum Vitae – English

1. Professional data/activity

Full name MAIGRET Bernard

Date of birth 1944

Country France

E-mail bernard.maigret@loria.fr

Institution LORIA – H. Poincaré University – UMR CNRS 6003

Present position Emeritus CNRS Research Director

Department Orpailleur group

Start date (month/year) 02/2010

Office address LORIA – Scientific Campus

P.O. box 239

City Vandoeuvre les Nancy Cedex

State/Province Lorraine

Country France

Zip code 54506

Phone number (33) 3 54 95 85 93

Extension

Fax number (33) 3 83 91 25 30

2. Academic background

Degree

Field of knowledge Chemical engineer

Start / End date 1965/1968

Engineer

Institution Ecole Nationale Supérieure de Chimie

city Strasbourg

Country France

Degree

Field of knowledge Docteur Ingénieur en Chimie Quantique

Start / End date 1968/1971

First PhD

Institution Paris 6 University

city Paris

Country France

Degree

Field of knowledge Docteur d’Etat es Sciences Physiques

Start / End date 1972/1975

Second PhD

Institution Paris 6 University

city Paris

Country France

3. Research interests

Field of Study

CNPq use

Molecular modeling

Structural bioinformatics

Drug design and discovery

Applied mathematics

4. Current position

Managerial and/or administrative activity

None presently

Research and Development

Drug design and discovery

omics of membrane receptors

Technical service/specialization

Virtual Screening – Chemogenomics – structural bioinformatics

Others

Teacher in molecular modeling

5. Work experience

5.1. Institution

Position

Activities

Local

Start - End date

Institut de Biologie Physico-Chimique Paris

Graduate fellow and next CNRS “attaché de recherches”

Quantum Mechanics

Laboratory of Quantum Chemistry

1968-1975

Medical Research Council Cambridge UK

PostDoc

Protein crystallography

Laboratory of Molecular Biology

1976-1977

Henri Poincaré University Nancy

CNRS “Chargé de Recherches”

Biomolecular simulations

Laboratory of Molecular Biophysics

1978-1984

Louis Pasteur University Strasbourg

CNRS “Chargé de Recherches” and next CNRS “Directeur de Recherches”

Molecular, biomolecular and material simulations Quantum Chemistry

Laboratory of Supramolecular Chemistry

1985-1992

Henri Poincaré University Nancy

CNRS “Directeur de Recherches”

Quantum Chemistry and Molecular simulations

Laboratory of Theoretical Chemistry (Head)

1993-1997

Henri Poincaré University Nancy

CNRS “Directeur de Recherches”

Membrane and membrane receptors simulations

UMR 7506 eDAM group (Head)

1998-2006

Henri Poincaré University Nancy

CNRS “Directeur de Recherches” And next CNRS “Emeritus Directeur de Recherches”

Structural Bioinformatics Drug design Chemogenomics and chemoinformatics

LORIA Orpailleur group

2007-present

6. Scientific, technological and artistic production

number

number

1. scientific articles in national scientific journals

none

6. papers presented in congresses, seminars, conferences, etc.

52

2. scientific articles in international scientific journals

191

7. participation in expositions, presentations, etc.

130

3. articles for scientific divulgement

2

8. motion pictures,  videos, audiovisual and media production

2

4. defended theses

2

9. patents

1

5. advised theses

25

10. books

none

7. Main publications : Relevant publications related to the project

Comparative genomics allowed the identification of drug targets against human fungal pathogens. ABADIO AK, KIOSHIMA ES, TEIXEIRA MM, MARTINS NF, MAIGRET B, FELIPE MS. BMC Genomics.,12,75 (2011) HIV-PDI: A Protein-Drug Interaction Resource for Structural Analyses of HIV Drug Resistance: 1. Concepts and Associated Database GHEMTIO L, SMAÏL-TABBONE M, DJIKENG A, DEVIGNES M, KEMINSE L, KELBERT P, FOKAM J, MAIGRET B, OUWE-MISSI-OUKEM-BOYER O J. Health Med. Informat., 2, 104, 1-10  (2011)   HIV-PDI: A Protein Drug Interaction Resource for Structural Analyses of HIV Drug Resistance: 2. Examples of Use and Proof-of-Concept GHEMTIO L, SOUCHET M, DJIKENG A, KEMINSE L, KELBERT P, RITCHIE W D, MAIGRET B, OUWE-MISSIOUKEM-BOYER O J. Health Med. Informat., 2, 105, 1-11  (2011) Community-wide blind assessment of methods for GPCR structure modeling and docking MICHINO M, ABOLA E, GPCR ASSESSMENT PARTICIPANTS (MAIGRET B is one of them), BROOKS CL, DIXON S, MOULT J, STEVENS RC, Nature Reviews Drug Discovery, 8, 455-463 (2009) Multiple-step virtual screening using VSM-G: overview and validation of fast geometrical matching enrichment. Beautrait, A., V. Leroux, M. Chavent, L. Ghemtio, M. D. Devignes, M. Smail-Tabbone, W. Cai, X. Shao, G. Moreau, P. Bladon, J. Yao, B. Maigret J. Mol. Model., 14,135 (2008) SHEF: a vHTS geometrical filter using coefficients of spherical harmonic molecular surfaces. Cai, W., J. Xu, X. Shao, V. Leroux, A. Beautrait, B. Maigret J. Mol. Model., 14, 393 (2008) Intersurf: Dynamics interface between proteins. N. RAY, X. CAVIN, J.C. PAUL et B. MAIGRET J. Mol. Graph Model., 23, 347 (2005) Protein-ligand recognition using spherical harmonics surfaces: towards a fast and efficient filter for large virtual throughput screening W. CAI, X. SHAO et B. MAIGRET J. Mol. Graph. Mod., 20, 313 (2002) Visualisation, management and integration of G Protein-coupled receptor related information : the Viseur program F. CAMPAGNE, J.-M. BERNASSAU et B. MAIGRET J. Computer-Aided Mol. Design,  13, 626 (1999) New alignment strategy for transmembrane proteins. M. CSERZO, J.M. BERNASSAU, I. SINOTRE et B. MAIGRET J. Mol. Biol., 243, 388-396 (1994)

8. Languages

Indicate your language proficiency:  P – poor      G - good      E - excellent

Language

speaking

reading

writing

Language

speaking

reading

writing

French

E

E

E

English

E

E

E

Brazilian

P

G

G